Vetstream header image and menu Click for a free trial
Constipation
print.gif Feedback
Contributors:

Introduction
  • Cause: prolonged gastrointestinal transit time of multiple etiologies.
  • Signs: tenesmus, anorexia, altered motions.
  • Diagnosis: signs, radiography.
  • Treatment: fecal softening, enemas, occasionally manual removal.
  • Prognosis: good for resolution of signs but may recur.
  • May progress towards megacolon Megacolon.
  • Severe megacolon as a result of chronic constipation can be unmanageable and owners may request euthanasia Euthanasia.


Presenting signs
  • Non-productive attempts to defecate.
  • Passage of very hard (desiccated) fecal pellets.
  • Anorexia.
  • Vomiting.
  • If associated with colitis Colitis, constipation may be interspersed with the passage of heterogeneous diarrhea often containing fresh blood.


Cost considerations
  • Surgical intervention of megacolon.
Pathogenesis Top


Predisposing factors
General
  • Foreign material in diet, eg hair, bones Intestine: foreign body - linear.
  • Intestinal lumen narrowing:
    • Pelvic fracture malunion .
    • Neoplasia (intraluminal, mural or extra-intestinal) Small intestine: neoplasia Large intestine: neoplasia.
    • Foreign body impaction.
  • Dehydration.
  • Reduced gastrointestinal motility:
    • Neurological dysfunction due to spinal injury.
    • Metabolic disease, eg hypercalcemia .
    • Dysautonomia Feline dysautonomia.
    • Drug-induced, eg anticholinergics, diuretics, opioids.
    • Inflammatory bowel disease Inflammatory bowel disease: overview (including some forms of colitis Colitis).
  • Behavioral - related to infrequent voiding:
    • Animal unwilling to posture, eg hip dysplasia.
    • Painful defecation, eg pelvic fracture, anal sacculitis Anal disease.
    • Unclear or unavailable litter tray.


Pathophysiology
  • Cats can retain feces in the colon for long periods without deleterious effects.
  • Prolonged retention arrows increases water resorption right_arrow harder drier feces.
  • Resorption of toxins may also occur right_arrow vomiting.
  • Vomiting can also result from vagal stimulation of vomiting center as a result of bowel wall stretching.
  • Diarrhea results from the ability of loose feces only to pass obstruction, or from inflammatory bowel disease Inflammatory bowel disease: overview.


Timecourse (incubation, duration)
  • Days to weeks for constipation to develop.
  • Predisposing factors may be present for years.

Diagnosis Top

Presenting problems
  • Tenesmus .


Client history
  • Straining.
  • Vocalization or discomfort at defecation attempts.
  • No motion passed or small amounts of liquid feces (owner may mistake problem for diarrhea), or very small amounts of very dry and hard feces.
  • Anorexia.
  • Depression.
  • Vomiting.


Clinical signs
  • Palpation of firm, distended colon.
  • Frequently dehydrated.


Diagnostic investigation
Radiography
  • See abdominal radiography Radiography: abdomen for technique.
  • Visualization of distended colon on abdominal radiograph Abdomen: obstipation and acquired megacolon - radiograph lateral.
  • May also visualize cause of impaction:
    • Pelvic malunion Pelvis: malunion and obstipation - radiograph VD.
    • Rectal mass or extra-intestinal compression.
Other
  • Digital palpation.


Confirmation of diagnosis
Discriminatory Diagnostic features
  • Signs.

Definitive Diagnostic features
  • Palpation of impacted colon.
  • Radiography.


Gross autopsy findings
  • Expose and examine entire colon by removal of ventral coxal bones by cutting cranially and caudally from each obturator foramen.
  • Include examination of all pelvic contents, plus coxo-femoral and hindlimb skeleton.
  • Collect autonomic ganglia, eg coeliacomesenteric ganglion between adrenals and aorta (fix tissue block 1 cm margin around each adrenal, since hard to locate ganglia).
  • Examine spinal cord and nerves to rule out neurological etiology.


Histopathology findings
  • See megacolon Megacolon.
  • Occasionally colonic ganglia have lymphocytic infiltrate - cause unknown.


Differential diagnosis
  • Urinary tenesmus Urethra: obstruction.
  • Colitis Colitis.
  • Neoplasia (colorectal) Small intestine: neoplasia Large intestine: neoplasia.
  • Small intestinal diarrhea .

Treatment Top
Initial symptomatic treatment
  • Fluid therapy Fluid therapy: overview to rehydrate animal (this also has the effect of rehydrating impacted feces).
  • Serial warm water enemas to soften mass of feces.
  • Colonic lubrication with water-soluble jelly/water mixture (may need to be administered under sedation Sedation or sedative protocol). Lactulose enemas may also be useful.


Standard treatment
  • Anesthesia General anesthesia: overview and forceps or surgical (in extreme cases) removal of impacted feces if fecal mass fails to soften adequately.
  • In some cases subtotal colonectomy may be required .
  • Manage underlying condition where possible.
  • Prokinetic agents, eg cisapride Cisapride (1-2 mg/kg PO BID-TID has been suggested as a starting dose - though doses as high as 5 mg/kg PO BID may be necessary).


Monitoring
  • Continued passage of normal formed stools.


Subsequent management

Prevention Top


Prophylaxis
  • Encourage regular defecation by frequent exercise.
  • Supplement dietary fiber or use stool modifying agents, eg peridale.
  • Oral laxatives, eg lactulose Lactulose.

Sequelae Top
Prognosis
  • Good for resolution of presenting problem.
  • Animals which are predisposed to development of constipation may suffer repeated episodes.


Expected response to treatment
  • Passage of normal stools.

Sources Top
Publications
Refereed papers
  • White R (2002) Surgical management of constipation. J Feline Med Surg. 4 (3), 129-138.
  • Smith M C et al (1996) Obstipation following ovariohysterectomy in a cat. Vet Rec 138 (7), 163.
  • McCauley M D (1996) Dosage consideration for cisapride. JAVMA 208 (2), 184.
  • Trout N J (1994) Obstipation secondary to coccygeal vertebral separation in a cat. Vet Rec 135 (20), 483.
  • Rosin F (1993) Megacolon in cats - the role of colectomy. Vet Clin North Am Small Anim Pract 23 (3), 587-594.
  • Muir P et al (1991) Megacolon in a cat following ovariohysterectomy. Vet Rec 129 (23), 512-513.
  • Matthiesen D T et al (1991) Subtotal colectomy for the treatment of obstipation secondary to pelvic fracture malunion in cats. Vet Surg 20 (2), 113-117.
  • Dimski D S (1989) Constipation - pathophysiology, diagnostic approach, and treatment. Semin Vet Med Surg Small Anim 4 (3), 247-254.
  • Rosin E et al (1988) Subtotal colectomy for treatment of chronic constipation associated with idiopathic megacolon in cats. JAVMA 193 (7), 850-853.
  • August J R (1983) Gastrointestinal disorders of the cat. Vet Clin North Am Small Anim Pract 13 (3), 585-597.


Vetstream contributor(s)

Back to top
© Copyright Vetstream

FELIS DIS02600

















































































Subscribers and trialists can view the additional links below and within theadjacent article. To trial our services click here:
Anal disease
Anus: atresia
Cisapride
Colitis
Colon: resection
Cystitis: bacterial
Enema
Euthanasia
Feline dysautonomia
Fluid therapy: overview
General anesthesia: overview
Inflammatory bowel disease: overview
Intestine: foreign body - linear
Lactulose
Large intestine: neoplasia
Megacolon
Organomegaly
Paraffin
Priapism
Prostate gland: disease
Radiography: abdomen
Rectum: stricture
Sacroiliac luxation
Sedation or sedative protocol
Small intestine: neoplasia
Sodium citrate
Sterculia
Urethra: obstruction
Vitamin D poisoning (cholecalciferol)
Abdomen: obstipation and acquired megacolon - radiograph lateral Link Pelvis: malunion and obstipation - radiograph VD Link
Please click on the links below to view this months other FOC content:
Click to subscribe
Copyright © Vetstream  Terms and Conditions  Privacy policy